Degassing of Biotech Devices incorporating Custom Quality Products

Degassing of Biotech Devices incorporating Custom Quality Products
Degassing of Biotech Devices incorporating Custom Quality Products
A degassing system consists of a vacuum chamber, a vacuum pump, and vacuum pump connection hardware. Such system is used to remove entrapped gasses from a liquid. A biotech customer of ours contacted us to design, manufacture, and deliver a custom vacuum degassing system which included a custom tray, wire feedthroughs, and BNC Vacuum feedthroughs.

Due to being a cGMP facility, our customer had stringent requirements which had to follow strict FDA Guidelines. The degassing process had to be recorded, monitored, validated, and repeatable across batches. The system we provided for them was an acrylic vacuum chamber with 14 inch Inside dimensions. This was a fully assembled system – once they received this, all they had to do is plug it in, no additional assembly was necessary. The vacuum pump we provided to them was a piston pump. Although not ideal, since the maximum achievable vacuum is not as high as compared to the rotary vane vacuum pump, it was chosen due to the fact that a piston pump is an oil free pump and does not emit oil mist. Furthermore, an oil free pump will not have the risk of oil contamination thru product degassing. This was a table top chamber meaning only a vacuum pump and vacuum pump was provided.

The vacuum chamber customization included, a QTY: 3 x #14 Gauge wires, a QTY: 9 x #22 Gauge wires, QTY: 2 x BNC Coaxial Feedthrough, and a vacuum pump 0.25 inch NPT Feedthrough. Each feedthrough is fully vacuum sealed where they can be operated during full vacuum degassing operation without the loss of vacuum performance. A digital Vacuum gauge was also provided so that the degassing process can follow cGMP guidelines such as being recordable and reputable due to the fact that a digital vacuum gauge has a much higher accuracy and precision as compared to a dial vacuum gauge. If you are looking for a degassing system, please take a look at our vacuum degassing systems made by Sanatron. There are several standard systems available and we will be happy to customize these for you as per your requirements. Contact us for more information.

Did you know that we carry a many more products?

We make Robustly Designed and Quality Engineered Systems. You should check out some of our other items we carry; click on the links below.

Internal Pressurization ASTM F2096 Leak Testing Systems
Internal Pressurization (ASTM F2096) Leak Testing Systems are instruments that are used during the Quality Control process to discover leaks in sealed packages. As opposed to the vacuum bubble leak test, where the specimen is subjected to a vacuum, the internal pressurization integrity test creates a pressure difference and drives the air through a leak by internally pressurizing the specimen. Our Internal Pressurization Leak Testing Systems are designed and built to conform to the ASTM F2096 Protocol Standard.
Belt Drive Rotary Vane Vacuum Pumps
A Belt Drive Rotary Vane Pump is almost identical to a Direct Drive Rotary Vane Pump. The only difference between the two is that the belt drive Rotary Vane Vacuum Pump is driven by a belt. There are several advantages why a belt drive vacuum pump would be preferable. One of these reasons is that the belt drive Rotary Vane Vacuum Pump runs at a slower RPM therefore the temperature created is lower, the wear and tear is less, and the overall lifetime of the pump is longer. The disadvantages are a lower CFM and performance.
Our Work: Leak Quality Testing and Quality Control of Packets
Quality Control during Production runs is a very important procedure you must perform on your manufactured products. This is especially critical is you are an FDA manufacturer where regulatory compliance is important and necessary. Our Vacuum Chambers are specifically built to assist you meet your Quality Control and Regulatory compliance needs.
Related Articles: Selecting a Proper Vacuum Pump for your Acrylic Vacuum Chamber
In this article we will talk about Vacuum Pumps - but also about other equipment which is used to produce vacuum inside a closed system or chamber. We will talk about the workings of a vacuum pump, vacuum generation, pump down, pump horsepower. This article is intended to provide you a practical guide which should help you select the appropriate vacuum pump for your system.