Degassing of Biotech Devices incorporating Custom Quality Products

Degassing of Biotech Devices incorporating Custom Quality Products
Degassing of Biotech Devices incorporating Custom Quality Products
A degassing system consists of a vacuum chamber, a vacuum pump, and vacuum pump connection hardware. Such system is used to remove entrapped gasses from a liquid. A biotech customer of ours contacted us to design, manufacture, and deliver a custom vacuum degassing system which included a custom tray, wire feedthroughs, and BNC Vacuum feedthroughs.

Due to being a cGMP facility, our customer had stringent requirements which had to follow strict FDA Guidelines. The degassing process had to be recorded, monitored, validated, and repeatable across batches. The system we provided for them was an acrylic vacuum chamber with 14 inch Inside dimensions. This was a fully assembled system – once they received this, all they had to do is plug it in, no additional assembly was necessary. The vacuum pump we provided to them was a piston pump. Although not ideal, since the maximum achievable vacuum is not as high as compared to the rotary vane vacuum pump, it was chosen due to the fact that a piston pump is an oil free pump and does not emit oil mist. Furthermore, an oil free pump will not have the risk of oil contamination thru product degassing. This was a table top chamber meaning only a vacuum pump and vacuum pump was provided.

The vacuum chamber customization included, a QTY: 3 x #14 Gauge wires, a QTY: 9 x #22 Gauge wires, QTY: 2 x BNC Coaxial Feedthrough, and a vacuum pump 0.25 inch NPT Feedthrough. Each feedthrough is fully vacuum sealed where they can be operated during full vacuum degassing operation without the loss of vacuum performance. A digital Vacuum gauge was also provided so that the degassing process can follow cGMP guidelines such as being recordable and reputable due to the fact that a digital vacuum gauge has a much higher accuracy and precision as compared to a dial vacuum gauge. If you are looking for a degassing system, please take a look at our vacuum degassing systems made by Sanatron. There are several standard systems available and we will be happy to customize these for you as per your requirements. Contact us for more information.

We have many more resources on our website that you should check out

We treat our customers well by Over-Delivering on our Promises (reason why we are Highly Rated on Google My Business). Check out some of our other items we carry that you can combine/integrate with your systems or projects.

Altitude Package ASTM D6653 Leak Testing Systems
Altitude Package (ASTM D6653) Leak Testing Systems, or Testing Systems which test the effect of higher altitude on packages are vacuum systems that consist of a vacuum chamber, a vacuum controller, and a vacuum pump. The goal of these package testing systems is intended to test and investigate the effects of higher altitudes on the seal integrity, package quality, or container closure integrity.
Ethernet Vacuum Feedthroughs
Ethernet Vacuum Feedthroughs are Vacuum Rated Ethernet connectors that enable you to run ethernet cables into your vacuum chamber. Simply connect your ethernet connector to the outside of the vacuum chamber and another ethernet cord from the inside and run it into your part present inside your vacuum chamber.
Our Work: Vacuum Storage of Pharmaceutical Products and Medical Supplies
A pharmaceutical manufacturer contacted us to build them a large vacuum storage system for their pharmaceutical products. They were looking for as much footprint as possible which is why they got a two-chamber system from us. They needed a total of 6 shelves per chamber including trays. Finally, they were looking to have both chambers to be placed on a table frame assembly with lockable swivel casters. What you are seeing is a two chamber system, each chamber is our 20 inch cube acrylic vacuum chamber, front load hinged door. Each chamber can be accesses independently while the other is under vacuum. The trays can be easily loaded and unloaded. This whole system can also be moved to anywhere in their facility.
Related Articles: Seal and Package Integrity Testing of Vacuum Sealed Packages
How do you test the seal of vacuum sealed packages? If you are vacuum sealing your packages, you are faced with a challenge when it comes to seal testing. How do you know that your process is consistently creating a good seal? How can you be sure that the vacuum inside you package will hold for the required amount of time?