Degassing of Biotech Devices incorporating Custom Quality Products

Degassing of Biotech Devices incorporating Custom Quality Products
Degassing of Biotech Devices incorporating Custom Quality Products
A degassing system consists of a vacuum chamber, a vacuum pump, and vacuum pump connection hardware. Such system is used to remove entrapped gasses from a liquid. A biotech customer of ours contacted us to design, manufacture, and deliver a custom vacuum degassing system which included a custom tray, wire feedthroughs, and BNC Vacuum feedthroughs.

Due to being a cGMP facility, our customer had stringent requirements which had to follow strict FDA Guidelines. The degassing process had to be recorded, monitored, validated, and repeatable across batches. The system we provided for them was an acrylic vacuum chamber with 14 inch Inside dimensions. This was a fully assembled system – once they received this, all they had to do is plug it in, no additional assembly was necessary. The vacuum pump we provided to them was a piston pump. Although not ideal, since the maximum achievable vacuum is not as high as compared to the rotary vane vacuum pump, it was chosen due to the fact that a piston pump is an oil free pump and does not emit oil mist. Furthermore, an oil free pump will not have the risk of oil contamination thru product degassing. This was a table top chamber meaning only a vacuum pump and vacuum pump was provided.

The vacuum chamber customization included, a QTY: 3 x #14 Gauge wires, a QTY: 9 x #22 Gauge wires, QTY: 2 x BNC Coaxial Feedthrough, and a vacuum pump 0.25 inch NPT Feedthrough. Each feedthrough is fully vacuum sealed where they can be operated during full vacuum degassing operation without the loss of vacuum performance. A digital Vacuum gauge was also provided so that the degassing process can follow cGMP guidelines such as being recordable and reputable due to the fact that a digital vacuum gauge has a much higher accuracy and precision as compared to a dial vacuum gauge. If you are looking for a degassing system, please take a look at our vacuum degassing systems made by Sanatron. There are several standard systems available and we will be happy to customize these for you as per your requirements. Contact us for more information.

Did you know that we carry a many more products?

Our clients prefer to work with us because we are Experts in Custom Fabrication (especially Polymer Fabrication). You should check out some of our other items we carry; click on the links below.

Portable Vacuum Chamber and Pump Systems
We carry a wide range of portable vacuum chamber and pump systems. A Portable Vacuum Chamber and Pump system is placed onto a frame structure and lockable swivel casters which enable you to move your vacuum chamber and pump system around your facility. Our portable vacuum systems are very popular among businesses that are constantly growing, evolving, or sharing. Our portable vacuum systems are moved with ease from location to location.
BNC Vacuum Feedthroughs
Coaxial Vacuum Feedthroughs are vacuum rated BNC connectors that enable you to run BNC from outside of vacuum chamber towards inside of the vacuum chamber without disturbing the vacuum. Triaxial Vacuum Feedthroughs, just like coax vacuum feedthroughs, will enable you to run Triax Connections from outside towards the inside of the vacuum chamber without disturbing the vacuum levels inside the vacuum chamber.
Our Work: Custom Vacuum Chamber with Blank Plate
You are looking at our standard Acrylic Vacuum Chamber, Hinged Door with Clamps. There is only one difference; this vacuum chamber has a blank acrylic plate that is connected to and aluminum plate which in turn is anchored to the side wall of the acrylic vacuum chamber. This blank plate is there to enable our client to add vacuum feedthroughs to the side wall in the future
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This article will talk about how to test the seal integrity of food bars. You will understand what you will need to do in order to ensure good seal quality. This article covers the seal integrity testing of Breakfast bars, Chocolate candy bars, Crisped rice bars, Energy bars, Granola bars, Health bars, Protein bars, Fruit and Nut Bars, Meal Replacement Bars or any other food bar sealed with a flow wrapper.